Study Title
The Impact of Diet and Physical Activity on Bone Health in Children and Adolescents
Principal Investigator
Patrizia Proia, Alessandra Amato, Patrik Drid, Darinka Korovljev, Sonya Vasto, Sara Baldassano
Affiliation
University of Palermo, Italy; University of Novi Sad, Serbia; University of Palermo, Italy
Start Date
Not specified
End Date
Not specified
Study Objective
To investigate the effects of diet and physical activity on bone health in children and adolescents, focusing on dietary influences (macronutrients and micronutrients) and the role of physical activity in bone development.
Short Abstract
This review explores the role of nutrition and physical activity in influencing bone health during childhood and adolescence. The study found that diet, particularly in relation to macronutrients such as proteins, and micronutrients like calcium and vitamin D, plays a crucial role in optimizing bone mass. Physical activity, especially weight-bearing and high-impact exercises, significantly contributes to bone mineral density (BMD). The review also discusses hormonal regulation, including parathyroid hormone and gut peptides, in bone remodeling and their interaction with diet and physical activity.
Study Design
Systematic review
Population
Children and adolescents
Sample Size
Not specified
Inclusion Criteria
Studies that explore the effects of diet and physical activity on bone health in children and adolescents
Exclusion Criteria
Studies not focusing on both diet and physical activity's effects on bone health
Intervention/Exposure
Dietary factors (protein, fat, carbohydrates, calcium, vitamin D) and physical activity interventions (weight-bearing, high-impact exercises)
Outcome Measures
Bone mineral density (BMD), bone mineral content (BMC), bone strength, and other markers of bone health
Funding Source
Not specified
Collaborating Institutions
University of Palermo, University of Novi Sad
Ethics Approval
Not applicable (systematic review)
Publication Status
Published in Frontiers in Endocrinology, September 2021
Keywords
Bone health, diet, physical activity, children, adolescents, macronutrients, micronutrients, bone mineral density
Data Collection Methods
Systematic review of studies published in databases such as PubMed, Web of Science, and other relevant journals
Primary Data Availability
Not applicable
Contact Information
Sara Baldassano (