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Nutrition Interactions with COVID-19

These articles provide information on what is currently known about the nutrition interactions with the virus and its effects on the human body. A strong focus is also to understand how nutritional circumstances or interventions might mitigate the infections’ harm, both acutely and in the long term. The collection also showcases, and welcomes, good quality evidence studying the combination of diet and lifestyle factors that may strengthen immunity and susceptibility to the virus.
 

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  • Study Status: Published
  • Study Type: Review
  • Study Location: UK

Study Title
Nutritional Parameters and Outcomes in Patients Admitted to Intensive Care with COVID-19: A Retrospective Single-Centre Service Evaluation.

Principal Investigator
Timothy Eden, Shane McAuliffe, Dominic Crocombe, Jonathan Neville, Sumantra Ray.

Affiliation
Hammersmith Hospital, NNEdPro Global Centre for Nutrition and Health, Imperial College Healthcare NHS Trust.

Start Date
March 2020.

End Date
May 2020.

Study Objective
To investigate the effect of body mass index (BMI), glycaemic control, and vitamin D status on outcomes in adult patients with COVID-19 admitted to an intensive care unit (ICU).

Short Abstract
This retrospective study analyzed the association between nutritional parameters such as BMI, glycaemic control, and vitamin D status with outcomes in ICU patients with COVID-19. The study found that increased BMI, impaired glycaemic control, and low vitamin D levels were common, but no significant statistical correlation was observed with mortality outcomes. The results suggest a need for further research into the role of nutritional markers in COVID-19 outcomes.

Study Design
Retrospective review of electronic patient records from a single-center ICU in London.

Population
Patients admitted to an ICU in West London with confirmed COVID-19.

Sample Size
72 patients.

Inclusion Criteria
Patients admitted to the ICU with confirmed COVID-19 (SARS-CoV-2 positive).

Exclusion Criteria
None.

Intervention/Exposure
Evaluation of patient BMI, glycaemic control (HbA1c), and vitamin D levels on admission.

Outcome Measures
Primary: Mortality rate.
Secondary: Duration of ICU stay, time intubated, ICU-related morbidity.

Funding Source
No specific funding declared.

Collaborating Institutions
Hammersmith Hospital, NNEdPro Global Centre for Nutrition and Health, Imperial College Healthcare NHS Trust.

Ethics Approval
Not mentioned (service evaluation).

Publication Status
Published in BMJ Nutrition, Prevention & Health, August 2021.

Keywords
COVID-19, nutritional status, ICU, glycaemic control, BMI, vitamin D, mortality.

Data Collection Methods
Data were collected retrospectively from electronic patient records.

Primary Data Availability
Available upon request from the first author, Dr. Timothy Eden.

Contact Information
Dr. Timothy Eden, timothy.eden@nhs.net.