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Clinical Nutrition

The Clinical Nutrition special collection aims to advance our understanding of the role of nutrition in clinical practice. We invite submissions that investigate the efficacy of nutritional interventions in improving clinical outcomes, optimising patient care, and enhancing quality of life for individuals with acute or chronic medical conditions.
 

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Low-Bacterial Diet in Cancer Patients: A Systematic Review

Details
Category: Clinical Nutrition
Hits: 16
ID: 117
  • Study Status: Published
  • Study Type: Review
  • Study Location: Global

Study Title
Low-Bacterial Diet in Cancer Patients: A Systematic Review

Principal Investigator
Sofia Matteucci, Giulia De Pasquale, Manuela Pastore, Emanuela Morenghi, Veronica Pipitone, Fanny Soekeland, Riccardo Caccialanza, Beatrice Mazzoleni, Stefano Mancin

Affiliation
IRCCS Humanitas Research Hospital, Humanitas University, University of Applied Sciences, Fondazione IRCCS Policlinico San Matteo

Start Date
Not specified

End Date
Not specified

Study Objective
To evaluate the effects of the low-bacterial diet (LBD) in cancer patients, specifically those with neutropenia, and its impact on infection rates, mortality, and quality of life.

Short Abstract
This systematic review analyzes the use of the low-bacterial diet (LBD) in neutropenic cancer patients. The review found that while LBD is commonly recommended to reduce foodborne infections, it did not show a significant reduction in infection or mortality rates and was associated with a negative impact on quality of life due to dietary restrictions and reduced food variety.

Study Design
Systematic review of studies from 2015 to 2023

Population
Cancer patients with neutropenia, particularly those with hematologic malignancies undergoing chemotherapy

Sample Size
3469 participants from 12 studies

Inclusion Criteria
Studies on LBD in cancer patients with neutropenia, measuring infection rates, mortality, and quality of life

Exclusion Criteria
Studies involving pediatric populations or those with incomplete data

Intervention/Exposure
Low-bacterial diet (LBD) vs. standard diet (SD)

Outcome Measures

  • Infection rates (including bacteremia, pneumonia)
  • Mortality rates
  • Quality of life (e.g., incidence of diarrhea, nausea, weight loss)

Funding Source
No external funding specified

Collaborating Institutions
IRCCS Humanitas Research Hospital, University of Applied Sciences, Fondazione IRCCS Policlinico San Matteo

Ethics Approval
Not specified

Publication Status
Published in Nutrients (2023)

Keywords
Neutropenic diet, low-bacterial diet, cancer, hematologic malignancies, infection prevention, quality of life

Data Collection Methods
Systematic search across PubMed, CINAHL, EMBASE, and Cochrane Library using keywords related to neutropenic diet, infection prevention, and cancer

Primary Data Availability
Not applicable

Contact Information
Sofia Matteucci: This email address is being protected from spambots. You need JavaScript enabled to view it.