Study Title
Genotype-informed nutrition counselling in clinical practice.
Principal Investigator
Martin Kohlmeier, Emmanuel Baah, Matthew Washko, Kelly Adams.
Affiliation
University of North Carolina at Chapel Hill, School of Medicine and Gillings School of Global Public Health, UNC Nutrition Research Institute.
Start Date
October 2023.
End Date
Not applicable (ongoing use of genotype-informed algorithms).
Study Objective
To integrate genotype-informed nutrition counselling into clinical practice and improve dietary treatment outcomes by tailoring advice based on individual genetic predispositions.
Short Abstract
The study discusses how genotype-specific dietary interventions can improve patient outcomes by tailoring nutrition advice to genetic profiles. Specific nutrigenetic algorithms have been validated, providing clinicians with practical tools for addressing conditions like obesity, cardiovascular disease, and vitamin deficiencies. This approach contrasts with the traditional one-size-fits-all method and offers a more personalized approach to nutrition counselling.
Study Design
Practice guidelines based on validated nutrigenetic algorithms.
Population
Adults, with specific focus on individuals of European and African ancestry.
Sample Size
Not applicable (guidelines).
Inclusion Criteria
Patients with available genetic information relevant to nutrition interventions.
Exclusion Criteria
Children and adolescents (insufficient evidence).
Intervention/Exposure
Genotype-informed dietary guidance for conditions like obesity, hypertension, and hyperlipidaemia.
Outcome Measures
Improved patient outcomes through targeted nutrition interventions based on genetic predispositions.
Funding Source
Supported by the UNC Nutrition Research Institute.
Collaborating Institutions
University of North Carolina at Chapel Hill, UNC Nutrition Research Institute.
Ethics Approval
Not applicable (guidelines and review).
Publication Status
Published in BMJ Nutrition, Prevention & Health, December 2023.
Keywords
Genotype-informed nutrition, precision nutrition, nutrigenetics, personalized dietary advice, clinical practice guidelines.
Data Collection Methods
Review of existing literature and development of practice guidelines.
Primary Data Availability
Not applicable.
Contact Information
Dr. Martin Kohlmeier,